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  • Recipient Sponsor Title Institution Mentor

    2022

    Adil Akkouch, MS, PhD

      Development of smart antibacterial mesh for abdominal wall repair. Western Michigan University Homer Stryker  

    2020

    Jessica Weaver, MD, PhD

      Intestinal Inflammation and bacterial translocation in traumatic brain injury UC San Diego  

    2019

    Joseph S. Fernandez-Moure MD MS

      Biomimetic Proteo-Lipid Nanovesicles Protect Against Septic Leukocyte-Endothelial Dysfunction Duke University Medical Center  

    2018

    Elliot Williams, MD

        University of California - San Diego  Todd Costantini

    2017

    Aaron Williams

        University of Michigan Health System  Hasan B. Alam

    2016

    Eleanor A. Fallon

       The impact of PD-1:PD-L1 on cellular dysfunction in murine neonatal abdominal sepsis Brown University Alfred Ayala & Daithi Heffernan

    2015

       
     
    Kristina L. Guyton, MD  

     Elucidating the Genetic Basis by which Commensal Enteroccus faecalis evolves into a tissue destructive pathogen causing intestinal anastomotic leak

    University of Chicago  

    2014

    Anthony J. Lewis, MD  

     

    University of Pittsburgh  

    2013

    Kendell Sowards   Changes in Insulin Resistance and Prediction of Infection in Trauma Patients Vanderbilt University Medical Center  

    2012

    Kaushik Mukherjee, MD Foundation   Vanderbilt University Medical Center Addison K. May, MD

    2011

    Gina Howell, MD Foundation Calcium/ Calmodulin-Dependent Kinases (CAMK) Regulate Organ Dysfunction Durine Murine Endotoxemia University of Pittsburgh School of Medicine Matthew Rosengart, MD, MPH

    2010

             

    2009

             

    2008

    Ward Richardson, MD Merck The Role of Nucleotide Oligomerization Domain 2 in the Pathogenesis of Necrotizing Enterocolitis. University of Pittsburgh David J. Hackam, M.D.
    Goro Tajima, MD AstraZeneca The Functional Significance of Upregulated CD 14 Gene and Protein Expression after Injury. Brigham and Womens Hospital James Lederer PhD
    Mae Fatima Cantos, MD Pfizer Organ Injury after Hemorrhagic Shock: The Role of Toll-Like Receptor 4 in Macrophage Priming. St. Michael’s Hospital Ori D. Rotstein, M.D.

    2007

    Catherine Hunter, MD Merck Interaction of E. sakazakii with enterocytes and its role in enterocytes and its role in enterocolitis Childrens Hospital of Los Angeles Henri Ford, MD
    Andreas Lenz, M.D. Pfizer IL-10 and defective early innate immunity in a murine model of chronic peritonitis University of Louisville William Cheadle, M.D.

    2006

    Rahul J. Anand, M.D. Merck & Co., Inc The role of gap junctions in modulating phagocytosis during microbial invasion University of Pittsburgh School of Medicine David J. Hackam, M.D.

    2005

    Traci L. Hedrick, M.D. Merck & Co., Inc CpG ONN effect of human neutrophil University of Virginia Robert Sawyer, M.D.
    Patrick S. Tawadros, M.D. Pfizer Role of Ceramide production in oxidant induced LPS signaling University of Toronto Ori D. Rotstein, M.D.
    Fredric M. Pieracci M.D. Wyeth A randomized controlled trial of the effects of iron supplementation on anemia and risk of infection in critical illness Weill Medical college of Cornell University Philip S. Barie, M.D.

    2004

    Mark R. Hemmila, M.D. Cubist The role of lipopolysccharide binding protein in the pathogenesis of bacterial pneumonia University of Michigan Stewart Wang, M.D.
    Norma M. Edwards, M.D.  Merck & Co., Inc   University of Tennessee Health Science Center  

    2003

    Rachael G. Khadaroo, M.D. Pfizer The cellular and molecular mechanisms regulating oxidative stress-induced priming of the macrophage University of Toronto Ori D. Rotstein, M.D.
    Melanie J. Scott, M.D. Merck & Co., Inc The role of natural killer cells in polymicrobial sepsis University of Louisville William Cheadle, M.D.
    Paul S. Vietzen, M.D. Wyeth Biological basis of endotoxin antagonism by LALF University of Minnesota  

    2002

    Priscilla McAuliffe, M.D. Pfizer Modifying dendritic cell phenotype through adenovirus and AAV-2 mediated gene transfer and its subsequent evaluation in murine polymicrobial sepsis University of Florida Linc Moldawer, M.D.
    Kaye M. Nembhard, M.D. Merck & Co. Protective role of nitric oxide (NO) and NF-kB in liver transplant ischemia/reperfusion injury University of Pittsburgh David A. Geller, M.D.
    David Urbach, M.D. Foundation Effect of increased cholecystectomy use on the incidence of acute complications of gallbladder disease University of Toronto Ori D. Rotstein, M.D.

    2001

    Prosanto K. Chaudhury, M.D. Merck & Co., Inc. The role of PECAM-1 in regulating neutrophil (PMN) transmigration and vascular leakage in sepsis McGill University Nicolas Christou, M.D.
    Kay M. Nembhard, M.D. Pfizer Protective role of nitric oxide (NO) and NF-kB in liver transplant ischemia/reperfusion injury University of Pittsburgh David A. Geller, M.D.
    Giuseppe Papia, M.D. Astra Zeneca Failed upregulation of counterinflammatory molecules: their role in lung injury and inflammation following shock/resuscitation University of Toronto Ori D. Rotstein, M.D.
    Julie E. Park, M.D. Roche The role of arginine and T-lymphocytes in wound healing under normal and septic conditions Johns Hopkins University Adrian Barbul, M.D.

    2000

    Ketan Sheth, M.D. Pharmacia Corporation Are post-trauma neutrophils immunostimulatory and anti-inflammatory? University of Massachusetts Paul Bankey, M.D.
    Jose L. Pascual, M.D. Merck & Co., Inc. Mechanisms for decreased hemorrhage and sepsis-induced tissue injury after resuscitation with hypertonic saline McGill University Nicolas Christou, M.D.
    Brad Feltis, M.D. Aventis Effect of clostridium difficile on bacterial penetration of the intestinal epithelial barrier University of Minnesota Carol L. Wells, M.D.
    Daniel P. Raymond, M.D. Pfizer The role of the CpG bacterial DNA motif in the counter-inflammatory response to extra-cellular infection in humans University of Virginia Robert Sawyer, M.D.
    Eric S. Hungness Dura Pharmaceuticals Mucosal and enterocyte IL-6 production during sepsis and endotoxemia and the role of the transcription factor NF-kB University of Cincinnati Per Olof Hasselgren
    Joy Collins, M.D. Astra Zeneca The role of nitric oxide in the post-hemorrhage immunosuppressed state University of Pittsburgh Timothy R. Billiar, M.D.

    1999

    Eric S. Hungness Dura Pharmaceuticals Mucosal and enterocyte IL-6 production during sepsis and endotoxemia and the role of the transcription factor NF-kB University of Cincinnati Per Olof Hasselgren
    Allen Feltis Rhone-Poulene-Rorer Effect of clostridium difficile on bacterial penetration of the intestinal epithelial barrier University of Minnesota Carol L. Wells, M.D.
    George D. Oreopoulos, M.D. Pfizer Use of hypertonic saline to prevent hepatic ischemia-reperfusion injury University of Toronto Ori D. Rotstein, M.D.
    Evan P. Nadler, M.D. Roche Mechanism of nitric oxide-mediated enterocyte apoptosis University of Pittsburgh Henri R. Ford, M.D.
    Edmund K. Ng, M.D. Zeneca ICI II-1 receptor-mediated affects of C. difficile toxins on colonocyte function Saint Louis University John E. Mazuski, M.D.

    1998

    Vaishali D. Schuchert, M.D. Bristol-Myers Squibb Nitric oxide regulation of hepatic dysfunction in sepsis University of Pittsburgh Brian G. Harbrecht, M.D.
    James J. Kraatz, M.D. Roche Catecholamine modulation of bacterial growth in intraabdominal surgical infection Hennepin County Medical Center Michael A. West, M.D.
    Avery B. Nathens, M.D., Ph.D. Wyeth-Ayerst Evaluation of the use of ascorbic acid in polytrauma patients as an antioxidant University of Washington Ronald Maier, M.D.
    Lorenzo Ferri, M.D. Pfizer Mechanisms for the reduced polymorphonuclear neutrophil exudation in sepsis-induced systemic Inflammation McGill University Nicolas Christou, M.D.
    Edward Lin, M.D. Zeneca ICI Regulation FAS/CD95 signal transduction in activated immunocytes Robert Wood Johnson Medical School Stephen F. Lowry, M.D.

    1997

    Carl A. Weiss III, M.D. Hoechst Marion Roussel Development and characterization of PBIderived-novel endotoxin antagonist University of Minnesota David Dunn, M.D.
    Julia J. Jones, M.D. Zeneca ICI Redox regulation of endothelial cell activation: role in organ injury University of Toronto Ori D. Rotstein, M.D.
    Mary Beth Harler, M.D. Pfizer Regulation of phagocytic functions by the wound microenvironment Brown University Jorge Albina, M.D.
    Scott W. Gibson, M.D. 3M   University of Cincinnati J. Wesley Alexander, M.D.
    James J. Kraatz, M.D. Roche Catecholamine modulation of bacterial growth in intraabdominal surgical infection Hennepin County Medical Center Michael A. West, M.D.
    Richard D. Klein, M.D. Bristol-Myers Squibb   University of Michigan Stewart Wang, M.D.

    1996

    Margo Shoup, M.D. Bristol-Myers Squibb Influence of gram-negative infection on the bone morrow myeloid G-CSF receptors in a murine model of thermal injury Loyola University Richard Gamelli, M.D.
    Martin Moon, M.D. Zeneca ICI Interleukin-6 and acute phase protein synthesis in mucosa of small intestine during sepsis and endotoxemia University of Cincinnati Per Olof Hasselgren
    Carl A. Weiss III, M.D. Hoechst Marion Roussel Development and characterization of PBIderived-novel endotoxin antagonist University of Minnesota David Dunn, M.D.
    Edward M. Boyle, M.D. 3M Regulation of endothelial cell activation genes University of Washington Tim Pohlman, M.D.

    1995

    Edward M. Boyle, M.D. 3M Regulation of endothelial cell activation genes University of Washington Tim Pohlman, M.D.
    Avery B. Nathens, M.D. SmithKline Beecham A novel liver-dependent immunoregulatory Cascade University of Toronto John C. Marshall, M.D.
    Gregory C. Lukaszewicz, M.D. Bristol-Myers Squibb Control of lung glutamine synthetase expression during infection and inflammation MCH-Harvard Wiley W. Souba, M.D.
    James M. Wong, M.D. Marion Merrell Down   University of Pittsburgh Richard L. Simmons, M.D.

    1994

    Avery B. Nathens, M.D. Lederle A novel liver-dependent immunoregulatory Cascade University of Toronto John C. Marshall, M.D.
    Tory Meyer, M.D. SmithKline Beecham The role of TNF, IL-1and IL6 in the regulation of intestinal synthesis University of Cincinnati Per-Olaf Nystrom
    Paul Freeswick, M.D. 3M Cytokine synergy in the transcriptional regulation of inducible nitric oxide synthase University of Pittsburgh Timothy R. Billiar, M.D.
    Kevin Johnson, M.D. Zeneca ICI Noradrenergic stress in macrophage dysfunction during TPN University of Washington Scott Helton, M.D.
    Mary Bridget Carter, M.D. Marion Merrell Down Pulmonary microvascular function in sepsis University of Louisville Neal Garrison, M.D.

    1993

    Alfred Santos, M.D. Upjohn Metabolic Response to Endotoxin: Does the route of feeding modify the inflammatory response? Brigham and Women's Hospital D. Wilmore, M.D.
    Daniel G. Hafenrichter, M.D. Stuart Pharmaceuticals Endotoxin tolerance protects against lethal endotoxemia by altering mediators produced by Kupffer cells Washington University M.W. Flye, M.D.
    Gretchen M. Ahrendt, M.D. E.R. Squibb & Sons Intestinal proline absorption in sepsis Johns Hopkins University A. Barbul, M.D.
    Tory Meyer, M.D. SmithKline Beecham The role of TNF and IL-1 University of Cincinnati Per-Olaf Nystrom
    Mary Bridget Carter, M.D. Marion Merrell Down Pulmonary microvascular function in sepsis University of Louisville Neal Garrison, M.D.
    Patricia A. Abello, M.D. 3M Oxygen free radical scavengers prevent programmed cell death in endothelial cells sequentially exposed to endotoxin and heat shock in vitro Johns Hopkins University Timothy G. Buchman, M.D.

    1992

    Patricia A. Abello, M.D. 3M Interruption of gene expression for a cytoprotective protein results in apoptosis in endothelial cells Johns Hopkins University Timothy G. Buchman, M.D.
    David A. Rodeberg, M.D. E.R. Squibb & Sons Loss of neutrophil adhesion molecules in burn patients as a predisposing factor in sepsis and infection University of Cincinnati Glen Warden, M.D.
    W.D. Bary Clements Marion Laboratories The effects of obstructive jaundice in kupffer cell function Queens University, Belfast Brian J. Rowlands, M.D.
    Peter Tin Yan Chu, M.D. UpJohn Intercellular and the role of liver in the pathogenesis of multiorgan failure University of Toronto John C. Marshall, M.D.
    Mark J. Lieser, M.D. Stuart Pharmaceuticals The role of gamma-interferon in an animal model of endotoxin-induced acute lung injury Wayne State University Steven D. Tennenberg, M.D.

    1991

    Addison K. May, M.D. 3M Characterization of bacterial virulence traits in intraabdominal infections University of Virginia Timothy Pruett, M.D.
    Thomas K. Lee, M.D. Marion Merrell Dow      
    David A. Rodenberg, M.D. E.R. Squibb & Sons The characterization of neutrophil subpopulation in burn and trauma patients as a predisposing factor to infection and sepsis University of Cincinnati Glen Warden, M.D.
    Colleen M. Ryan, M.D. Marion Merrell Down Monoclonal Monoclonal antibody targeted photolysis of burn wound infection Massachusetts General Hospital John Burke, M.D.

    1990

    Colleen M. Ryan, M.D. Marion Merrell Down Monoclonal Monoclonal antibody targeted photolysis of burn wound infection Massachusetts General Hospital John Burke, M.D.
    Addison K. May, M.D. 3M Characterization of bacterial virulence traits in intraabdominal infections University of Virginia Timothy Pruett, M.D.
    Thomas K. Lee, M.D. E.R. Squibb & Sons Bacterial translocation in small bowel transplantation University of Pittsburgh Wolfgang Schraut, M.D.
    Carolyn Cody, M.D. Stuart Pharmaceuticals Correlation of antibody binding to gram negative microorganisms with in vivo protective capacity University of Minnesota David Dunn, M.D.

    1989

    Leopoldo Sanchez-Cantu, M.D. 3M Functional capacity of the APC in the DTH skin reaction in surgical patients McGill University Nicolas Christou, M.D.
    Brent R. W. Moelleken, M.D. Marion Merrell Dow Comparison of activation states, complement receptors and oxidative function in neutrophils of peripheral blood, musculocutaneous and random pattern flaps University of California, San Francisco Thomas Hunt, M.D. and Steve Mathes, M.D.
    Ronald Dennis Curran, M.D. Stuart Pharmaceuticals Hepatocyte-Kupffer cell interactions in surgical sepsis University of Pittsburgh Richard Simmons, M.D.

    1988

    Matthew Brunson, M.D.  3M Manipulation of arachidonic acid metabolism as a means of augmenting transfusion-induced immunosuppresion while reducing risk of infection following transplantation University of Cincinnati J. Wesley Alexander, M.D.
    Donna Lynn Dyess, M.D. Marion Merrell Dow Immunological response to opportunistic pathogens in burn patients University of South Alabama Joseph Coggin, M.D.
    Ronald Dennis Curran, M.D. Stuart Pharmaceuticals Hepatocyte-Kupffer cell interactions in surgical sepsis University of Pittsburgh Richard Simmons, M.D.

    1987

    John Edward Mazuski, M.D 3M Effects of septic mediators on acute phase protein synthesis by isolated mouse hepatocytes University of Minnesota Frank B. Cerra, M.D.
    Jean I. Tchervenko, M.D. Johnson & Johnson Dietary and pharmacological manipulation of arachidonic acid metabolism as a means of augmenting transfusion-induced immunosuppression University of Cincinnati J. Wesley Alexander, M.D.
    Thomas K. Takayama, M.D. Stuart Pharmaceuticals Increased sensitivity of trauma patient monocytes to bacterial cell wall products University of Massachusetts Carol Miller Graziano, Ph.D.

    1986

    John Edward Mazuski, M.D 3M Effects of septic mediators on acute phase protein synthesis by isolated mouse hepatocytes University of Minnesota Frank B. Cerra, M.D.
    Arthur Revhaug, M.D. Johnson & Johnson   Harvard Medical School  

    1985

    Richard K. Simmons, M.D. Johnson & Johnson      
    J. Paul Waymack, M.D. 3M   Shriners Burn Institute  

    1984

    James M. Watters, M.D. Johnson & Johnson The induction of inflammation in humans and its metabolic effects Harvard Medical School, Brigham & Women's Hospital Douglas W. Wilmore, M.D.
    J. Paul Waymack, M.D. 3M   Shriners Burn Institute